What is the Hydroxylamine hydrochloride?

Hydroxylamine hydrochloride is Colorless or off-white crystalline solid, while it's Molecular Formula is H3NO . HCl. Colorless or off-white crystalline solid Hydroxylammonium-chloride is a reducing agent in photography; in synthetic and analytical chemistry; as an antioxidant for fatty acids and soaps; in textiles;in medicine; controlled reduction reactions; non-discoloring short stoppers for synthetic rubbers; reagent for enzyme reactivation;powerful reducing agent; converts aldehydes and ketones to oximes and acid chlorides to hydroxamic acids; catalyst, swelling agent,and copolymerization inhibitor in polymerization processes; in floor lacquers and as an antioxidant for fatty acids and soaps.

What is the CAS number for Hydroxylamine hydrochloride?

The CAS number of Hydroxylamine hydrochloride is 5470-11-1.

What is Hydroxylamine hydrochloride (5470-11-1) used for?

Hydroxylamine hydrochloride is a reducing agent that is routinely used for the deacetylation of SATA to form free sulfhydryls (Figure 1), for cleavage of protein cross‐linkers that contain carbonyl groups (i.e. EGS) and for mutagenesis of plasmid DNA.Hydroxylamine converts aldehydes and ketones (carbonyls) to their oxime derivative in weak bases, therefore cross‐linkers and other compounds with carbonyl groups are cleavable with Hydroxylamine hydrochloride.SATA and SATP are modification reagents that add a sulfhydryl group to primary amines on biomolecules. The initial modification results in the addition of an acetyl‐protected sulfur enabling storage of the biomolecule. To generate a free sulfhydryl the biomolecule is treated with hydroxylamine to remove the protecting acetyl group (see figure).EGS and sulfo‐EGS are homobifunctional, succinimidyl ester, amine reactive crosslinkers that are resistant to cleavage by denaturants used in SDS‐PAGE conditions, but may be cleaved with hydroxylamine.InChI:InChI=1/ClH.H3NO/c;1-2/h1H;2H,1H2

Hydroxylamine hydrochloride

Basic information

Product Name:Hydroxylamine hydrochloride
CasNo.:5470-11-1
MF:H₃NO^.HCl
MW:69.4909

Physical and Chemical Properties

Purity:99%
Boiling Point:155-158 °C
Packing:Colorless or off-white crystalline solid
Throughput:

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Product Details

CasNo： 5470-11-1

MF： H₃NO^.HCl

Appearance： Colorless or off-white crystalline solid

Factory Supply High Purity 5470-11-1 with Cheap Price, Buy Reliable Quality Hydroxylamine hydrochloride

Molecular Formula:H3NO^.HCl
Molecular Weight:69.4909
Appearance/Colour:Colorless or off-white crystalline solid
Vapor Pressure:179mmHg at 25°C
Melting Point:155-158 °C
Boiling Point:56.5 °C at 760 mmHg
PSA：46.25000
Density:1.67 g/mL at 25 °C
LogP:0.83660

Hydroxylamine hydrochloride(Cas 5470-11-1) Usage and Factory

Hydroxylamine hydrochloride is an organic molecular entity. A colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide. Hydroxylamine•HCl is a reducing agent that is routinely used for the deacetylation of SATA to form free sulfhydryls, for cleavage of protein cross-linkers that contain carbonyl groups (i.e. EGS) and for mutagenesis of plasmid DNA. Hydroxylamine hydrochloride and hydroxylammonium chloride are two different names for the same chemical compound, represented by the formula NH₂OH·HCl. The compound consists of hydroxylamine (NH₂OH) combined with hydrochloric acid (HCl). Orchid Chemical Supplies Ltd was established in 2009.After more than 15 years of business accumulation, we have established good business relationships with over 25500 major factories in China, can quickly and efficiently connect with high-quality and reliable manufacturers. We distrubitor hydroxylamine hydrochloride and hydroxylamine sulfate.

InChI:InChI=1/ClH.H3NO/c;1-2/h1H;2H,1H2

5470-11-1 Relevant articles

Transamidation of Primary Amides with Amines Using Hydroxylamine Hydrochloride as an Inorganic Catalyst

C. Liana Allen, Benjamin N. Atkinson, Jonathan M. J. Williams

Angewandte Chemie International Edition > 51 > 6 > 1383 - 1386

A method for the transamidation of primary amides with primary or secondary amines provides access to secondary and tertiary amides, by utilizing catalytic quantities of hydroxylamine hydrochloride to activate the chemically robust primary amide group (see scheme). A mechanism of primary amide activation through a hydrogen‐bonding complex is proposed.

A New Method for Fast Preparation of Highly Surface-Enhanced Raman Scattering (SERS) Active Silver Colloids at Room Temperature by Reduction of Silver Nitrate with Hydroxylamine Hydrochloride

Nicolae LeopoldBernhard Lendl*

, J. Phys. Chem. B 2003, 107, 24, 5723–5727

Reduction of silver nitrate with hydroxylamine hydrochloride at alkaline pH and at room temperature yields highly sensitive SERS colloids within a short time. Changing the mixing order and rate of the two involved solutions, silver nitrate and hydroxylamine hydrochloride containing sodium hydroxide, one can control the size and dispersion of the produced colloids.